Development of Mulberry Leaf Extract for Suppressing Postprandial Blood Glucose Elevation
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Effects of Mulberry Leaf Extract Rich in 1-Deoxynojirimycin on Blood Lipid Profiles in Humans
Mulberry leaves are rich in 1-deoxynojirimycin (DNJ), an inhibitor of α-glucosidase. We previously showed that DNJ-rich mulberry leaf extract suppressed elevation of postprandial blood glucose in humans. The objective of this study was to evaluate the effects of DNJ-rich mulberry leaf extract on plasma lipid profiles in humans. An open-label, single-group study was conducted in 10 subjects with...
متن کاملAcute intake of mulberry leaf aqueous extract affects postprandial glucose response after maltose loading: Randomized double-blind placebo-controlled pilot study
1756-4646/$ see front matter 2013 Elsevi http://dx.doi.org/10.1016/j.jff.2013.04.015 * Corresponding authors. Tel.: +82 2 970 6740 E-mail addresses: [email protected] Mulberry leaf extract was investigated as a potent alpha-glucosidase inhibitor, especially for individuals with prediabetes. We evaluated the effect of the ingestion of mulberry leaf aqueous extract (MLAE) on postprandial glu...
متن کاملEffect of mulberry leaf extract with enriched 1‐deoxynojirimycin content on postprandial glycemic control in subjects with impaired glucose metabolism
UNLABELLED Aims/Introduction: The glucose analogue, 1-deoxynojirimycin (DNJ), found in mulberry (Morus alba) leaves, is a promising α-glucosidase inhibitor. We evaluated the effect of the ingestion of mulberry leaf extract with enriched DNJ content on postprandial hyperglycemia in subjects with impaired glucose metabolism. MATERIALS AND METHODS In study 1, we carried out a randomized, doub...
متن کاملThe effect of 8 weeks of combined exercises with supplemental consumption of mulberry leaf extract on the serum levels of fibroblast growth factor 21, glucose and insulin in elderly men with type 2 diabetes
Introduction and purpose: Fibroblast growth factor 21 is proposed as a therapeutic target for type 2 diabetes. The aim of this study was the effect of 8 weeks of combined exercises along with the consuming of mulberry leaf extract on the serum levels of glucose, insulin and fibroblast growth factor 21, in elderly men with type 2 diabetes. Materials and methods: In this semi-experimental study,...
متن کاملPostprandial hypoglycemic effect of mulberry leaf in Goto-Kakizaki rats and counterpart control Wistar rats
Postprandial hypoglycemic effect of mulberry leaf (Morus alba L.) was compared in two animal models: Goto-Kakizaki (GK) rats, a spontaneous non-obese animal model for type II diabetes, and their counterpart control Wistar rats. First, the effect of a single oral administration of mulberry leaf aqueous extract (MLE) on postprandial glucose responses was determined using maltose or glucose as sub...
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تاریخ انتشار 2017